Securing a Private Intranet?

crustythecrab asks: "My company wants to take a web-based data management system I wrote which runs on a closed network not connected to the internet and put it out on the net so everyone can access it remotely. The number one issue of course is security, and I've been asked to write a paper on how to make the system 'secure' in order to convince management that it will be safe to proceed. But the question runs through my mind: How secure is 'secure'? I'm running all UNIX, no Windows of anything on the server side, and I'll certainly recommend a VPN, but since nothing is 100% secure, I was wondering what the current state of the art in 'Intranet' security is. Are there any novel new concepts out there. Or do you just put up a VPN and hope for the best?"