How to Easily Make Custom Linux Install ISOs?

Jason Tilke asks: "I recently read an article which discusses HP's LinuxCOE v4. We've been wanting a system to make rolling out custom but standardized systems (in terms of package selection) and LinuxCOE seems to fit the bill. Are there any alternative that'll spit out custom ISOs which our non-technical staff can use to install a complete Linux system? Has anyone had any positive/negative experience with LinuxCOE? Are there any precautions/steps we should take to prevent us from tripping over our new changes?"